Zool Sci. However, it is important to note that these gene regulatory models are hypothetical and that they require experimental testing before firm conclusions are drawn. Steroid signaling and temperature-dependent sex determination — reviewing the evidence for early action of estrogen during ovarian determination in turtles.
Subfertility and defective folliculogenesis in female mice lacking androgen receptor. Administering estradiol at male-producing temperatures generates females that are physiologically identical to temperature-produced females. The compound is presumably carried through the shell, absorbed by the chorioallantoic vasculature, and transported to the embryo.
These observations lead to broader questions about sex-determining mechanisms. Genetics 1 — Researchers should also endeavor to test the hypothesis that these genes are involved in sex determination. Hormone Research.
Dmrt1 expression in response to estrogen treatment in a reptile with temperature-dependent sex determination. This article has been cited by other articles in PMC. These chemicals block the conversion of testosterone to estradiol during development so each sex offspring can be produced at all temperatures.
Constitutive heterochromatin and nucleolus organizer regions in Bufo and Hyla. Blurring the edges in vertebrate sex determination. Mol Gen Genomics. Sex determination in mammals — before and after the evolution of SRY. Expression of these proteins was similar in gonads from embryos incubated at male- and female-determining temperatures.